Scientific Advisory Board

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Assistant Professor of Pathology & Immunology

William K. Decker, Ph.D. is an Assistant Professor in the Department of Pathology & Immunology at Baylor College of Medicine in Houston, Texas. He is an internationally recognized expert in dendritic cell biology, cancer immunology and immunotherapy, and Th-1 immunity. Dr. Decker is a prinicipal Advisor to APAC Biotech’s scientific advisory board and offers his scientific opinion of dendritic cell immunotherapy. Dendritic cell immunotherapy has long been anticipated to be an important weapon in the fight against cancer. Dendritic cells are the master regulatory cells of the adaptive immune response; hence all immunoregulatory decisions, including those pertaining to anticancer responses, start with the dendritic cell. Dendritic cells live in the periphery where they serve as immune sentinels, constantly sampling the antigenic milieu and presenting antigenic peptides of this milieu on the cell surface. Upon detection of an inflammatory stimulus or “danger signal”, dendritic cells mature and migrate to the lymph nodes where they function by presenting antigens to CD4+ and CD8+ T-lymphocytes. These primed lymphocytes then migrate into the periphery where they seek out and destroy cells presenting the same antigens against which they were primed. The concept of providing dendritic cells to the patient for cancer therapy is meant to mimic the natural function of dendritic cells in vivo. To perform this procedure, white blood cells are removed from the patient and differentiated into dendritic cells in an ex vivo tissue culture system. Once generated, the dendritic cells are exposed to antigens derived from patient tumor cells after which they are matured and reintroduced into the patient to prime downstream immune responses. While this paradigm sounds simple in theory, it has proven highly complex in practice.

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Chairman, Cancer Institute- Division of Medical Oncology & Haemotology, Medanta-The Medicity, Gurgaon

Dr. Vaid is the Chairman, Cancer Institute- Division of Medical Oncology & Haemotology, Medanta-The Medicity, Gurgaon. He has been conferred Padma Shree award by the President of India for contribution to the field of medicine in 2009. He is a renowned oncologist of the country and member of various national and international professional bodies. Dr. Vaid has worked as an independent Consultant for the last 18 years. As a team leader in Medical Oncology, his involvement has been in diverse areas like routine clinical work in Haemato-oncology and solid tumours, tumour board decision making, and bone marrow transplant. He has had keen interest and involvement in drug trials. Dr. Vaid has authored a number of publications, research papers and abstracts and has been actively involved in organizing various seminars, workshops and conferences throughout the country. Dr. Vaid has also conducted more than 40 international and national studies in clinical research. He has the unique distinction of having carried out the first 25 bone marrow transplants in any private sector hospital in North India.

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Senior Consultant & Head of the Department of Oncology at Apollo Hospital, Bangalore

Dr. Bapsy is Senior Consultant & Head of the Department of Oncology at Apollo Hospital, Bangalore. Previously she was Head of the Department of Medical Oncology at Kidwai Oncology Hospital, Bangalore. Dr. Bapsy holds the unique distinction of being the first woman in India to obtain D.M. in (Medical Oncology). Bangalore. She has more than 25 years of experience in the field of Medical Oncology as well Teaching. Some of her awards include Paul Harris Award bur Rotary (2002), Senior Research Fellow, Oxford University, Oxford, UK (2005) and many more. She has authored more than 117 scientific publications in various National and International Journals. Member of various professional bodies viz. Indian Medical Association, Indian Society for Oncology, European School of Medical Oncology to name a few. Dr. Bapsy was the chief monitor of phase II clinical trials of the Dendritic Cell preparation developed by Apac Biotech

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Director, Urology at Saket City Hospital, New Delhi

Dr. Mohanty is currently Director, Urology at Saket City Hospital, New Delhi. He was previously Special DGHS, Govt. of India and Professor in Department of Urology at Safdarjang Hospital, New Delhi. He was formerly Medical Superintendent and Head of the department of Urology, Safdarjang Hospital, New Delhi. Dr. Mohanty has published more than 70 research papers and recipient of various fellowships and awards, which include the WHO fellowship 1996, INSA Fellowship 2003, IMA silver jubilee oration award 2005, rashtriya ratan award with gold medal 2006 etc. Dr. Mohanty is also an expert member to various government agencies namely Ministry of Defence, Govt. of India in Urology, Expert to Min. of Health & Family Welfare, Expert to UPSC in Urology, Examiner to M.Ch and DNB- Urology.

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Dr. Vanaja Konduri

Ph. D. Molecular & Human Genetics

Dr. Vanaja Konduri received her Ph.D. in Molecular and Human Genetics from the University of Queensland in Brisbane, Australia. After subsequent advanced training in plant genetics and developmental biology, Dr. Konduri received training in tumor immunology With Drs. William Decker and Jonathan Levitt and Baylor College of Medicine in Houston, Texas. In her work as a tumor immunologist, Dr. Konduri has made many outstanding contributions to both dendritic cell and T-cell biology and is an inventor on numerous important patents in the field. She remains on the faculty at Baylor College of Medicine and hold adjunct faculty appointments at the University of Houston and Houston Community College.

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Clinical Advisor

Dr Mehra is the National Professor (endowed chair of the ICMR) and ex-Dean of the All India Institute Of Medical Sciences (AIIMS) in New Delhi .